7th International Conference on HIV Treatment and Prevention Adherence

Antiretroviral therapy can inhibit viral replication and reduce viral load to a point where viral particles are undetectable in the blood of infected individuals. Significant and sustained suppression of HIV replication is associated with improved clinical outcomes. However, these benefits are only tenable when adherence to precise dosing schedules is rigorous and other requirements are closely followed. Partial or poor adherence can lead to the resumption of rapid viral replication, poorer survival rates, and virus mutation to treatment-resistant strains of HIV. Similarly, adherence to antiretroviral-based prevention interventions will be critical to achieving the promise that pre-exposure prophylaxis (PrEP) and other biomedical interventions hold to dramatically curb HIV transmission rates among at-risk populations.

Co-hosted by the International Association of Physicians in AIDS Care (IAPAC) and the National Institute of Mental Health (NIMH), the 7th International Conference on HIV Treatment and Prevention Adherence provided a forum where the state-of-the-science for HIV treatment and biomedical prevention adherence research was presented, discussed, and translated into evidence-based approaches. The 2.5-day program allowed healthcare and human service professionals to examine scientifically sound and practical strategies to enhance adherence to HIV treatment and biomedical prevention interventions in a variety of domestic and international settings.

Following are the presentations delivered at the 7th International Conference on HIV Treatment and Prevention Adherence – uploaded daily in real-time. The conference organizers request that any use of these presentations should include citations to both their presenting authors and relevant conference information (e.g., 7th International Conference on HIV Treatment and Prevention Adherence, June 3-5, 2012, Miami).


SUNDAY, June 3, 2012


Guidelines for Improving Entry into and Retention in Care and Antiretroviral Adherence for Persons with HIV
Melanie Thompson, MD

James D. Scott, PharmD, MEd

Michael Mugavero, MD, MHSc

K. Rivet Amico, PhD

Michael J. Stirratt, PhD

Addressing the Achilles’ Heel of HCV Clinical Management with Direct-Acting Antivirals
Christopher O’Brien, MD

Robert Gross, MD, MSCE

Jeffrey Weiss, PhD

MEMORIAL LECTURE – Antiretroviral Treatment is Prevention
Myron Cohen, MD

TREATMENT ADHERENCE IN DAILY LIFE: Perspectives from People Living with HIV
Moderator: Robert H. Remien, PhD
Panelists: Moisés Agosto-Rosario; Sherwood Epps; Dab Garner; Quintara LadyQueen-Lane; Maria T. Mejia; Kathleen Reed-Cabrera; Jorge Luis Suarez-Suarez


MONDAY, June 4, 2012

KEYNOTE ADDRESS – Antiretroviral-Based HIV Treatment and Prevention Strategies: Advancing Science to Practice
Jared Baeten, MD, PhD

PLENARY – Constructing Antiretroviral Regimens to Overcome Imperfect Adherence

Amanda Corbett, PharmD


ORAL ABSTRACT SESSION 1 – Addressing Biomedical Prevention Adherence

79934 – Performance of and Adherence to the Wisebag for Potential Monitoring of Gel Applicator Use in Durban, South Africa
Ariane van de Straten presenting

80026 – High Adherence among HIV-1 Serodiscordant Couples in the Partners PrEP Ancillary Adherence Study
Jessica Haberer presenting

80028 – A Pilot Study of Daily Short Message Service (SMS) Surveys of Sexual Behavior and PrEP Use among Kenyan HIV-1 Serodiscordant Couples
Katie Curran presenting

80040 – The Spectrum of Engagement in HIV Prevention: Proposal for a Pre-Exposure Prophylaxis (PrEP) Cascade
Albert Liu presenting


ORAL ABSTRACT SESSION 2 – Mental Health and ART Adherence

79988 – Changes in HIV Providers’ Management of Depression after Integration of Treatment Support into Clinical Care
Brian Pence presenting

80001 – Individualized Texting for Adherence Building (iTAB) Improves cART Adherence in HIV-Infected Persons with Co-Occurring Bipolar Disorder
David Moore presenting

80064 – A Culturally Adapted Intervention to Treat Depression and ART Non-Adherence on the U.S.-Mexico Border: Final (Promising!) Results from a Pilot RCT
Jane Simoni presenting

80459 – Ziphamandla: The Feasibility and Usefulness of Implementing CBT-AD, a Cognitive Behavioral-Based Intervention for the Treatment of Adherence and Depression in a Primary ARV Clinic in Cape Town
Lena Andersen presenting


ORAL ABSTRACT SESSION 3 – Operations Research and Implementation Science

79426 – Electronic Medical Records and Same Day Patient Tracing Improves Clinic Efficiency and Adherence to Appointments in a Community-Based HIV/AIDS Care Program in Uganda
Stella Talisuna presenting

80016 – Secondary HIV Transmission Prevention Counseling and Antiretroviral Adherence Messages in an African Setting: A Time-Motion Study
Ann Kurth presenting

80135 – Pre-ART Adherence Counselling is Not Associated with Improved MEMS Adherence in Rural Uganda
David Bangsberg presenting

80466 – Bridging Practice and Research: A Survey of Evidence-Based Practices Used in HIV Care for Linkage, Retention and Adherence Support
K. Rivet Amico presenting


ORAL ABSTRACT SESSION 4 – Linkage to and Retention in HIV Care

79940 – Baseline Correlates of Retention in HIV Primary Care at Six HIV Clinics in the United States
Jason Craw presenting

80002 – Linkage and Engagement in Care as Predictors of Achieving and Maintaining Viral Suppression
Amanda Castel presenting

80029 – ART Ineligibility Confers High Risk of Poor Retention in the Pre-ART Period among Persons Newly Diagnosed with HIV Infection in Sierra Leone
Dan Kelly presenting

80464 – Early Adherence Patterns Predict Retention Rates in Large ART Cohort in Nigeria
Seema Meloni presenting


ORAL ABSTRACT SESSION 5 – Substance Use and ART Adherence

80047 – Improvements in Medication Adherence and Healthcare Utilization as Evidenced from a Pilot Intervention Combining Contingency Management and Behavioral Activation to Reduce Stimulant Use among HIV-Infected Individuals
Jennifer Mitty presenting

80081 – Injection Drug Users’ (IDUs’) and their Caregivers’ Social Network Factors Associated with IDUs’ Viral Suppression
Amy Knowlton presenting

80082 – Factors Associated with Non-Adherence to Antiretroviral Therapy among Patients Attending HIV Care and Treatment Clinics in Kenya, Namibia, and Tanzania
Harriet Nuwagaba-Biribonwoha presenting

80461 – Intentional Non-Adherence to Antiretroviral Medications among Alcohol Drinkers: Prospective Study of Interactive Toxicity Beliefs
Seth Kalichman presenting


ORAL ABSTRACT SESSION 6 – Patient-Provider Perspectives, Communication, and Relationships

78354 – African Americans’ Perceptions of HIV Provider Cultural Competence that Promote Medical Self-Care and Antiretroviral Medication Adherence
Gina Gaston presenting

79372 – Barriers to Care among Patients with HIV in South Africa: Contrasts between Patient and Provider Perspectives
Laura Bogart presenting

80000 – The Quality of Patient-Provider Dialogue about Initiation of Antiretroviral Medications
Mary Catherine Beach presenting

80080 – Patient Satisfaction as an Innovative Method for Improving Adherence to HAART
Bich Dang presenting


PLENARY – Three Top-Rated Oral Abstracts

79956 – Measuring Retention in HIV Care: The Elusive Gold Standard
Michael Mugavero presenting

80044 – Psychosocial Predictors of Acceptability and Risk Compensation for Pre-Exposure Prophlyaxis (PrEP): Results from Three Studies of Critical Populations
Sarit Golub presenting

80457 – Data-Adaptive Super Learning to Predict Viral Rebound Based on Electronic Adherence Monitoring: An Analysis of the MACH-14 Cohort Consortium
Maya Petersen presenting


TUESDAY, June 5, 2011

PLENARY – The Facilitating Roles of the National HIV/AIDS Strategy and the Affordable Care Act in Improving Care Engagement and Treatment Adherence in the United States
Grant Colfax, MD

PLENARY – Addressing Mental Health, Substance Use, and HIV Treatment Adherence
Steven Safren, PhD


ORAL ABSTRACT SESSION 7 – Supporting PrEP Adherence

80031 – Evaluation and Process Outcomes from an Adherence Intervention to Support HIV Pre-Exposure Prophylaxis (PrEP) Adherence in HIV-Serodiscordant Couples in Uganda
Christina Psaros presenting

80037 – Enhancing Pre-Exposure Prophylaxis (PrEP) Adherence in Men who have Sex with Men: Determining Optimal Content for a PrEP Adherence Package
Wade Taylor presenting

80048 – Preference for Daily versus Intermittent PrEP Dosing among Substance-Enhancing Pre-Exposure Prophylaxis in Men who have Sex with Men: Determining Optimal Content for a PrEP Adherence Package
Matthew Mimiaga presenting

80467 – Integrated Next Step Counseling (iNSC): A Discussion-Based Sexual Health Promotion Conversation to Support Men who have Sex with Men (MSM) using Pre-Exposure Prophylaxis (PrEP) in the iPrEx Open Label Extension (iPrEx OLE)
K. Rivet Amico presenting


ORAL ABSTRACT SESSION 8 – ARV Regimanes, Adherence, and Viral Suppression

79321 – Real-World Adherence and Persistence to First-Line, Ritonavir-Boosted, Protease Inhibitor-Based Antiretroviral Regimens
Timothy Juday presenting

80042 – MEMS-Defined Treatment Interruptions Independently Predict HIV RNA Controlling for Average Adherence in Rural Uganda
Maya Petersen presenting

80074 – Differential Impact of Non-Adherence on Week 96 Outcomes in the Emtricitabine/Tenofovir DF (FTC/TDF) Subset of Pooled ECHO and THRIVE Studies Comparing RPV vs. EFV in Treatment-Na����ve, HIV-1-Infected Adults
Dushyantha Jayaweera presenting

80453 – Simultaneity and Adherence to Multiple Tablets Regimen among Subjects Starting Once-Daily Atazanavir/Ritonavir (ATV/RTV)-Based Therapy: The ANRS COPHAR 3 Study
Jean-Jacques Parienti presenting


ORAL ABSTRACT SESSION 9 – International Research in Priority Populations

79467 – Intervening to Increase Adherence among HIV-Positive Patients in Northern India
Deborah Jones presenting

79946 – Buddy System in Operationalizing Continuum of Care Intervention among Sex Workers in Mumbai,India
Samita Bhardwaj presenting

80057 – Adherence in Mobile Populations: Qualitative Study of ART for Refugees in Sub-Saharan Africa
Kelli O’Laughlin presenting

80063 – Women, ART, and Adherence: A Longitudinal Comparison of Antiretroviral Adherence by Gender
Cathy Puskas presenting


ORAL ABSTRACT SESSION 10 – ART Adherence Monitoring and Measurement

79952 – Lessons from Cognitive Testing of Self-Report Adherence Items
Ira Wilson presenting

80027 – Real-Time HIV Antiretroviral Therapy Adherence Monitoring among Adults and Children in Rural Uganda
Maya Petersen presenting

80033 – Is a Simple Self-Rating or Visual Analogue Scale (VAS) more Reliable than Prescription Refill (PR) Data as an Indicator of Non-Adherence in a Resource-Limited Setting in South Africa?
Hannelie (JC) Meyer presenting

80066 – Are Intervention (versus Control) Arm Participants in ART Adherence Promotion Interventions more Likely to Overestimate Adherence? Findings from the MACH14 Study
Jane Simoni presenting


ORAL ABSTRACT SESSION 11 – ART Adherence Interventions

79967 – Impact of Managed Problem Solving Antiretroviral Adherence Intervention on HIV Copy-Years
Robert Gross presenting

79984 – Results of an Online Social Support and Text Reminder ART Intervention
Keith Horvath presenting

79993 – Adherence and HIV Suppression after Behavioral Intervention in Patients with Elevated Viral Load
Neil Schneiderman presenting

80038 – A Computerized Tailored Information Intervention to Improve Health Literacy and Adherence in Persons with HIV Infection
Raymond Ownby presenting


ORAL ABSTRACT SESSION 12 – Child and Adolescent ART Adherence

79996 – Qualitative Comparison of Disclosure among Perinatally and Behaviorally HIV-Infected Adolescents
Idia Thurston presenting

80072 – Evaluation of the Feasibility and Validity of Short Message System (SMS) Text Messaging for Assessment of Antiretroviral Therapy Adherence among Youth Living with HIV/AIDS (YLH)
Nadia Dowshen presenting

80075 – Qualitative Analysis of Factors Influencing Adherence of Pediatric Patients to ART in Rural Uganda
Peter Olds presenting



Reducing Community Viral Load to Achieve Prevention
Moupali Das, MD, MPH

Managing HCV Infection and Treatment Adherence in the Direct-Acting Antiviral Era: Learning from the HIV Experience
Vincent Lo Re, MD, MSCE

CDC/HRSA Multisite Retention in Care (RiC) Study: Preliminary Results
Lytt Gardner, PhD
Gary Marks, PhD


CLOSING PLENARY – When Paradigms Shift: Challenges of a World in Which Combination Prevention is Our Standard, Most Everyone is Eligible for Lifetime ART, and Treatment is Prevention
Moisès Agosto-Rosario
Carl Dieffenbach, PhD
Massimo Ghidinelli, MD


2012 Conference Program and Abstracts
Click the images below to download the complete 2012 Program or the Poster Abstracts in PDF format.

Adherence Conference 2011 Program     Adherence Conference 2011 Poster Abstracts

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