How NNRTIs Work

OVERVIEW HIV attacks cells within the body’s immune system. To spread, the virus needs to enter these cells and make copies of itself. The copies are then released from these cells and infect other cells. Treatment with non-nucleoside reverse transcriptase inhibitors (NNRTIs) is one way… Read More

efavirenz (Sustiva)

WHAT IS EFAVIRENZ? Efavirenz, also known as EFV (brand name Sustiva), is a drug used as part of antiretroviral therapy (ART). The FDA approved efavirenz in 1998 as an antiretroviral drug (ARV) for people with HIV infection. Generic versions have been approved under PEPFAR. Efavirenz… Read More

etravirine (Intelence)

WHAT IS ETRAVIRINE? Etravirine, also known as ETR (brand name Intelence), is a drug used as part of antiretroviral therapy (ART). The FDA approved etravirine in 2008 as an antiretroviral drug (ARV) for people with HIV infection. Etravirine is manufactured by Janssen Therapeutics. Etravirine is… Read More

rilpivirine (Edurant)

WHAT IS RILPIVIRINE? Rilpivirine, also known as rilpivirine hydrochloride or RPV (brand name Edurant), is a drug used as part of antiretroviral therapy (ART). The FDA approved rilpivirine in 2011 as an antiretroviral drug (ARV) for people with HIV infection. Rilpivirine is manufactured by Janssen… Read More

doravirine (Pifeltro)

WHAT IS DORAVIRINE? Doravirine, also known as DOR (brand name Pifeltro), is a drug used as part of antiretroviral therapy (ART). The FDA approved doravirine in 2018 as an antiretroviral drug (ARV) for people with HIV infection. Doravirine is manufactured by Merck & Co. Doravirine… Read More